Endocrine Abstracts

Obesity is defined as a state of chronic low-grade inflammation. It is associated with pro-inflammatory activity of visceral adipose tissue, regarded as a neuroendocrine organ that secretes cytotoxins and other pro-inflammatory factors, impairing metabolic pathways. The corollary of these changes is the risk of developing comorbidities. There are many similarities in the mechanisms of ageing and in obesity. The process of ageing leads to the accumulation of pro-inflammatory fa...